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Monitor Intently (1)pentobarbital will decrease the extent or impact of osilodrostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases levels of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can cut down panobinostat stages by ~70% and result in proced

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